EBER In Situ Hybridization Experience In Hodgkin Lymphoma

Purpose
 Several studies suggest that the relation of Epstein-Barr virus (EBV) and Hodgkin lymphoma (HL). EBV HL associations are reported at rates ranging from 20% to 100% varies nationally regionally. In this study; in case Hodgkin's lymphoma, presence encoded RNA (EBER) by situ hybridization method it’s distribution according histopathological subtypes were investigated. 
 Methods
 We investigated Lymphoma diagnosed 107 adult cases between 2013 2017, which chromogenic with probe has been routine use evaluated retrospectively pathology reports.
 Results
 There 69 males 38. Nodular Sclerosis Classical (NSCHL) was most common (63 cases, 58,9%) followed Mixed Cellularity (MCCHL) (23 cases,21,5%). expressed 40 (45,4%). High association found NSCHL (50%) MCCHL (48%). None NLPHL positive EBER. Conclusion
 our series is histologic subtype higher percentages positivity as developed countries. Our study largest patients investigating relationship EBER country. For further comments more studies, particularly Turkey, needed determine actual epidemiological pattern region define role HL.